If you’ve been following the world of neuroscience, health, and fitness, you’ve likely heard of Andrew Huberman, Ph.D., a renowned neuroscientist and professor at Stanford University School of Medicine. His work focuses on understanding the brain’s function and its impact on our overall well-being. One of the many topics he’s delved into is the powerful supplement creatine, which is often associated with athletes and bodybuilders. In this article, we explore Andrew Huberman creatine insights and recommendations to help you make informed decisions about incorporating creatine into your health and fitness journey.

andrew huberman creatine

What is Creatine?

Creatine is a naturally occurring molecule in our body, synthesized primarily in the liver, kidneys, and pancreas. It plays a vital role in energy production, particularly for high-intensity activities such as strength training and sprinting. About 95% of our body’s creatine is stored in skeletal muscle, while the remaining 5% is distributed throughout the brain, liver, and kidneys.

Andrew Huberman on Creatine's Cognitive Benefits

While creatine is best known for its physical benefits, recent research has highlighted its potential cognitive advantages. Andrew Huberman has spoken extensively about the effects of creatine supplementation on cognitive performance, particularly under stressful or mentally demanding situations. Studies have shown that creatine can help improve short-term memory, cognitive processing speed, and mental endurance. This makes it a valuable supplement not only for athletes but also for anyone looking to enhance their mental performance in various aspects of life, such as work, academics, or problem-solving tasks.

Creatine's Physical Performance Benefits

The primary reason creatine has been a staple in the fitness world is due to its well-documented benefits for physical performance. Andrew Huberman emphasizes that creatine supplementation can:

  • Increase muscle strength and power
  • Enhance muscle endurance
  • Speed up recovery time after intense exercise
  • Promote muscle growth

These benefits make creatine an attractive option for athletes, bodybuilders, and fitness enthusiasts looking to improve their performance and achieve their goals more efficiently.

How Does Creatine Work?

Creatine’s primary function is to provide energy to cells, particularly muscle cells, by increasing the formation of adenosine triphosphate (ATP). ATP is the primary energy currency in our body, and when we engage in high-intensity activities, our body uses up ATP rapidly. Creatine helps replenish these ATP stores, allowing for sustained, high-intensity performance. Additionally, creatine may also play a role in reducing exercise-induced inflammation and promoting muscle protein synthesis, further contributing to its performance-enhancing effects.

Creatine Supplementation Dosage and Recommendations

When it comes to creatine supplementation, Andrew Huberman suggests following the standard guidelines for dosage and cycling. Typically, a loading phase is recommended, where you take around 20 grams of creatine per day for 5

to 7 days, divided into four equal doses. This phase helps saturate the muscles with creatine more quickly. Following the loading phase, you can transition to a maintenance phase, taking 3 to 5 grams of creatine daily to maintain elevated creatine levels in your muscles.

However, the loading phase is not mandatory, and some individuals may choose to skip it and begin with the maintenance dose of 3 to 5 grams per day. This approach will still lead to increased creatine levels in the muscles, but it will take longer to reach saturation.

Andrew Huberman also recommends cycling creatine supplementation, meaning you should take breaks from supplementation to allow your body’s natural creatine production to normalize. A common cycling strategy is to supplement with creatine for 8 to 12 weeks, followed by a 4-week break.

Choosing the Right Creatine Supplement

There are various forms of creatine available in the market, but Andrew Huberman advocates for creatine monohydrate, which is the most researched and proven form. When selecting a creatine supplement, look for reputable brands with third-party testing to ensure the product’s quality, purity, and safety. 

Potential Side Effects and Precautions

Creatine is generally considered safe for healthy individuals

when taken at recommended doses. However, some people may experience minor side effects such as gastrointestinal discomfort, bloating, or water retention. To minimize these side effects, consider starting with a lower dose and gradually increasing it, or splitting the dose throughout the day.

It is essential to consult with a healthcare professional before beginning any supplementation regimen, especially if you have pre-existing medical conditions or are taking medications. Additionally, proper hydration is crucial when supplementing with creatine, as it may increase the risk of dehydration or muscle cramps if you’re not consuming enough water.

Creatine for Vegans and Vegetarians

Andrew Huberman points out that creatine supplementation may be particularly beneficial for vegans and vegetarians, as their dietary intake of creatine is typically lower than that of non-vegetarians. Creatine is predominantly found in meat, fish, and poultry, which means that individuals who follow plant-based diets may have lower creatine levels in their muscles. Supplementing with creatine can help vegans and vegetarians optimize their cognitive and physical performance and support their overall health.


In summary, Andrew Huberman creatine insights reveal the potential of this powerful supplement for enhancing cognitive and physical performance across various populations. Whether you’re an athlete looking to improve your strength and endurance or an individual seeking to boost your mental acuity, creatine may be a valuable addition to your supplementation routine. By understanding the science behind creatine, adhering to proper dosage and cycling recommendations, and selecting a high-quality product, you can maximize the benefits of creatine while minimizing potential side effects.

Always remember to consult with a healthcare professional before starting any supplementation regimen, and ensure that your diet, exercise, and hydration practices are aligned with your health and fitness goals. By incorporating Andrew Huberman’s creatine insights into your wellness journey, you can unlock the full potential of this versatile supplement and experience its transformative effects on your body and mind.